Toronto trailed after James McCann scored for the Detroit Tigers in the seventh, but the Blue Jays came back to win.
Castellanos had three hits, including a three-run homer, and tied his career high with five RBIs Wednesday to lead Detroit over Cleveland.
The Indians have outscored the Tigers 76-24 in the season series. Cleveland leads Detroit by 7 1/2 games in the AL Central.
Detroit Tigers manager Brad Ausmus refuses to make excuses for his team’s woeful record against the Indians.
Justin Upton hit a two-run double and Ian Kinsler added his 200th career homer, helping the Detroit Tigers extend their winning streak.
Martinez hit three-run homers from both side of the plate and the Detroit Tigers rolled to a victory over the Tampa Bay Rays.
Cameron Maybin capped a dramatic eight-run ninth with a three-run double, and the Detroit Tigers overcame a five-run deficit to win.
Miguel Cabrera hit one of three homers for the Detroit Tigers in their win over the Miami Marlins on Wednesday.
Miguel Cabrera’s three-run homer highlighted a seven-run fifth inning for Detroit, and the Tigers went on to beat the Miami Marlins.
Justin Verlander allowed eight runs on nine hits and two walks in 4 2/3 innings.
Kipnis hit two of Cleveland’s four triples and the Indians continued their season-long dominance of the Tigers with a victory Friday night.
Pinch runner Cameron Maybin easily scored on a bases-loaded wild pitch by Steve Cishek with two outs in the 10th inning Thursday.
Steven Moya homered twice, and the Detroit Tigers withstood a shaky fifth inning from Michael Fulmer to beat the Seattle Mariners.
Mike Aviles drove in the tiebreaking run with an infield single in the eighth, and the Detroit Tigers went on to beat the Seattle Mariners.
Justin Upton hit a liner over the left-field wall in the 12th inning for his second homer of the game, lifting Detroit past the Mariners.