Jordan Zimmermann also extended his impressive scoreless innings streak to start the season.
The top-seeded Cavs put away the up-and-coming Pistons in the third quarter, outscoring them to protect home-court advantage.
The Lake County Captains came back after Monday night’s loss to beat the West Michigan Whitecaps on Tuesday.
Meanwhile, the Tigers did little to help out Shane Greene (1-1), who allowed seven runs in 4 1-3 innings.
Jackie Robinson’s daughter was in West Michigan to honor student who won an essay contest commemorating him.
Ondrej Palat scored with 2:59 left in the third period, lifting the Tampa Bay Lightning to a win over the Detroit Red Wings.
The West Michigan Whitecaps kicked off a seven-game homestand with a win on Monday.
With the regular season in the books, the Grand Rapids Griffins are turning their focus to the Calder Cup Playoffs.
Andreas Athanasiou and Henrik Zetterberg scored, Petr Mrazek made 16 saves and the Detroit Red Wings beat the Tampa Bay Lightning.
Jarrod Saltalamacchia and J.D. Martinez hit solo homers for Detriot. Ian Kinsler had a two-run homer and made a heads-up play in the fifth.
Kentavious Caldwell-Pope scored 21 and Marcus Morris 20 for the Pistons, making their first playoff appearance since 2009.
The Grand Rapids Griffins closed out the regular season Saturday night against the Bakersfield Condors.
Saltalamacchia hit a go-ahead two-run homer in the sixth inning and the Tigers rallied for a win over the Astros on Saturday.
Rasmus provided the offense with an RBI single and the Astros snapped a three-game skid with a win over the Detroit Tigers Friday.
Johnson scored a pair of third-period goals Friday night, helping the Tampa Bay Lightning beat the Detroit Red Wings in Game 2.